发明名称 1-PHENYLPYRROLE COMPOUNDS
摘要 The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1 -C3 alkyl group; R2 represents a hydroxy -C1 -C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1 -C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like,- R5 represents a sulfamoyl group or a C1-C3 alkylsulf onyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.
申请公布号 CA2736930(A1) 申请公布日期 2010.04.15
申请号 CA20092736930 申请日期 2009.10.07
申请人 EXELIXIS INC.;DAIICHI SANKYO COMPANY, LIMITED 发明人 NUSS, JOHN;WILLIAMS, MATTHEW;MOHAN, RAJU;MARTIN, RICHARD;WANG, TIE-LIN;TSURUOKA, HIROYUKI;AOKI, KAZUMASA;HONZUMI, MASATOSHI;ASOH, YUSUKE;SAITO, KEIJI;HOMMA, TSUYOSHI
分类号 C07D207/335;A61K31/405;A61P5/42;A61P7/10;A61P9/10;A61P9/12;A61P13/12 主分类号 C07D207/335
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