发明名称 |
1-PHENYLPYRROLE COMPOUNDS |
摘要 |
The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1 -C3 alkyl group; R2 represents a hydroxy -C1 -C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1 -C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like,- R5 represents a sulfamoyl group or a C1-C3 alkylsulf onyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.
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申请公布号 |
CA2736930(A1) |
申请公布日期 |
2010.04.15 |
申请号 |
CA20092736930 |
申请日期 |
2009.10.07 |
申请人 |
EXELIXIS INC.;DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
NUSS, JOHN;WILLIAMS, MATTHEW;MOHAN, RAJU;MARTIN, RICHARD;WANG, TIE-LIN;TSURUOKA, HIROYUKI;AOKI, KAZUMASA;HONZUMI, MASATOSHI;ASOH, YUSUKE;SAITO, KEIJI;HOMMA, TSUYOSHI |
分类号 |
C07D207/335;A61K31/405;A61P5/42;A61P7/10;A61P9/10;A61P9/12;A61P13/12 |
主分类号 |
C07D207/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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