发明名称 |
Immunotoxin fusion proteins and means for expression thereof |
摘要 |
The present invention described and shown in the specification and drawings provides novel recombinant DT-based immunotoxins, and, more specifically anti-T cell immunotoxin fusion proteins. Also provided are immunotoxins that can be expressed in bacterial, yeast, or mammalian cells. The invention also provides means for expression of the immunotoxin fusion protein.
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申请公布号 |
US7696338(B2) |
申请公布日期 |
2010.04.13 |
申请号 |
US20040296085 |
申请日期 |
2004.01.13 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;NOVARTIS AG |
发明人 |
NEVILLE, JR. DAVID M.;THOMPSON JERRY T.;HU HUAIZHONG;WOO JUNG-HEE;MA SHENGLIN;HEXHAM JONATHAN MARK;DIGAN MARY ELLEN |
分类号 |
C07H21/04;A61K47/48;C07K5/103;C07K7/06;C07K7/08;C07K14/34;C07K16/28 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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