An anthrax vaccine with alhydrogel as the adjuvant is presented in a composition formulated by mixing rPA with colloidal alhydrogel (alum) adjuvant to produce the final product, comprising 200 µg/ml rPA bound to 0.26% alhydrogel in phosphate buffered saline (PBS), said formulation containing an optimal concentration of phosphate. Methods of using the vaccines to treat or prevent infections are also presented.
申请公布号
WO2010038076(A1)
申请公布日期
2010.04.08
申请号
WO2009GB51293
申请日期
2009.10.02
申请人
PHARMATHENE UK LIMITED;WATKINSON, ALLAN;WOODHOUSE, DAVID;WILSON, ROBERT