| 发明名称 |
Cleavage of VEGF and VEGF receptor by wildtype and mutant MT-SP1 |
| 摘要 |
MT-SP1 mutein proteases with altered specificity for the target molecules they cleave can be used to treat human diseases, such as cancer. Cleaving VEGF or VEGFR at certain substrate sequences with wild-type and mutein MT-SP1 proteases can be used to treat pathologies associated with angiogenesis. |
| 申请公布号 |
AU2005244271(B2) |
申请公布日期 |
2010.04.08 |
| 申请号 |
AU20050244271 |
申请日期 |
2005.04.12 |
| 申请人 |
CATALYST BIOSCIENCES, INC. |
发明人 |
JACK NGUYEN;SANDRA WAUGH RUGGLES |
| 分类号 |
A61K38/00;C12N9/64 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 地址 |
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