| 发明名称 |
PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 8-[-METHYL]-8-PHENYL-1,7-DIAZA-SPIRO[4.5]DECAN-2-ONE COMPOUNDS |
| 摘要 |
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations. |
| 申请公布号 |
US2010087426(A1) |
申请公布日期 |
2010.04.08 |
| 申请号 |
US20080531859 |
申请日期 |
2008.03.20 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
MERGELSBERG INGRID;SCHERER DOMINIK HERMANN;HUTTENLOCH MONIKA ERIKA;TSUI HON-CHUNG;PALIWAL SUNIL;SHIH NENG-YANG |
| 分类号 |
A61K31/537;A61K31/438;A61P25/06;C07D221/20;C07D265/02 |
主分类号 |
A61K31/537 |
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