发明名称 |
Methods for synthesis and uses of inhibitors of ghrelin O-acyltransferase as potential therapeutic agents for obesity and diabetes |
摘要 |
The invention provides inhibitors of ghrelin O-acyltransferase, and methods of making and using them. In some embodiments, the invention provides bisubstrate analog inhibitors of ghrelin O-acyltransferase, which can be effective in treating, for example, obesity and diabetes mellitus. |
申请公布号 |
AU2009298892(A1) |
申请公布日期 |
2010.04.08 |
申请号 |
AU20090298892 |
申请日期 |
2009.09.18 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
PHILIP A. COLE;BRADLEY P. BARNETT;YOUSANG HWANG;JEF D. BOEKE |
分类号 |
C07K7/00;A61K38/08;A61K38/10;A61P3/10 |
主分类号 |
C07K7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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