| 发明名称 |
METHOD FOR THE PREPARATION OF ESCITALOPRAM |
| 摘要 |
A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as ChiralpakAD or ChiralcelOD. Novel chiral intermediates for the synthesis of Escitalopram made by said method are also provided. |
| 申请公布号 |
KR20100036387(A) |
申请公布日期 |
2010.04.07 |
| 申请号 |
KR20107004689 |
申请日期 |
2002.07.12 |
| 申请人 |
H. LUNDBECK A/S |
发明人 |
BECH SOMMER MICHAEL;NIELSEN OLE;PETERSEN HANS;AHMADIAN HALEH;PEDERSEN HENRIK;BROSEN PETER;GEISER FIONA;LEE JAMES;COX GEOFFEY;DAPREMONT OLIVIER;SUTEU CHRISTINA;ASSENZA SEBASTIAN P.;HARIHARAN SHANKAR;NAIR USHA |
| 分类号 |
C07D307/87;A61K31/343;A61P25/24;C07B;C07C215/32;C07C215/34;C07D |
主分类号 |
C07D307/87 |
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