COMPOSITION AND METHOD FOR TREATMENT OF PRETERM LABOR
摘要
The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. Said compositions and methods enhance gestation and therefore improve neonatal morbidity and mortality.
申请公布号
CA2738605(A1)
申请公布日期
2010.04.01
申请号
CA20092738605
申请日期
2009.09.24
申请人
THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVID ED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN;THE COOMBE LYING-IN HOSPITAL
发明人
O'NEILL, LUKE ANTHONY;O'LEARY, JOHN;DALY, SEAN;SCHARFE NUGENT, ANDREA