发明名称 |
NEW FUSION MOLECULE BASED ON NOVEL TAA VARIANT |
摘要 |
This invention provides novel carbonic anhydrase (CAIX) nucleic acid and peptide sequences, as well as related methods and compositions, including anti-cancer immunogenic agent(s) (e.g. vaccines and chimeric molecules) that elicit an immune response specifically directed against cancer cells expressing a CAIX antigenic marker. The novel CAIX variant and related compositions are useful in a wide variety of treatment modalities including, but not limited to protein vaccination, DNA vaccination, and adoptive immunotherapy. |
申请公布号 |
EP2117572(A4) |
申请公布日期 |
2010.03.31 |
申请号 |
EP20070869809 |
申请日期 |
2007.12.21 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LI, ZHENHUA;BELLDEGRUN, ARIE S. |
分类号 |
A61K38/00;A61K49/00;C07H21/04;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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