| 发明名称 |
INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 - NS4 PROTEASE |
| 摘要 |
The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds.
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| 申请公布号 |
SG159385(A1) |
申请公布日期 |
2010.03.30 |
| 申请号 |
SG20070001399 |
申请日期 |
2003.04.11 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
PITLIK JANOS;COTTRELL KEVIN M.;FARMER LUC J.;PERNI ROBERT B.;COURTNEY LAWRENCE F.;DRIE JOHN H. VAN;MURCKO MARK A. |
| 分类号 |
C12N9/99;A61K38/00;A61K38/04;A61P1/16;A61P31/12;A61P31/14;A61P37/02;A61P43/00;C07D209/42;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D417/12;C07D471/04;C07K5/04;C07K5/06;C07K5/10;C07K7/02;(IPC1-7):C07K5/10;A61K31/402;A61K31/403;A61K31/443;A61K31/501;C07D207/34;C07D403/14 |
主分类号 |
C12N9/99 |
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