| 发明名称 |
NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4-DIMETHOXY- BICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE |
| 摘要 |
<p>NEW PROCESS FOR THE RESOLUTION OF ENANTIOMERS OF (3,4-DIME THOXY- BICYCLO[4.2.0[OCTA-1,3,5-TRIEN-7-YL)NITRILE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE Process for the optical resolution of the compound of formula (I): by chiral chromatography. Application in the synthesis of ivabradine, of its addition salts with a pharmaceutically acceptable acid and of their hydrates.</p> |
| 申请公布号 |
SG159454(A1) |
申请公布日期 |
2010.03.30 |
| 申请号 |
SG20090051681 |
申请日期 |
2009.08.03 |
| 申请人 |
LES LABORATOIRES SERVIER |
发明人 |
LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;DRON DANIEL;GOJON ERIC;PHAN MARYSE |
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