Disclosed are mesalazine tablets and a method for their preparation. The mesalazine tablets comprise a tablet core, a first coating layer, and a second coating layer. The tablet core comprises mesalazine; the first coating layer comprises a cellulose derivative and/or povidone, and the second coating layer comprises methacrylic acid/methyl methacrylate copolymer and an anti-tack agent. The tablets show a high degree of uniformity and reproducibility and release mesalazine starting at pH 6.8 and are used in the treatment of colorectal diseases.
申请公布号
WO2009090484(A3)
申请公布日期
2010.03.25
申请号
WO2008IB03557
申请日期
2008.12.19
申请人
DISPHAR INTERNATIONAL BV;UGWOKE, MICHAEL, I.;CORSELLI, MARTA