METHOD OF ENHANCING TGF-BETA SIGNALLING

摘要

The present invention is directed to a method of enhancing TGF-ß signaling in a subject comprising administering to said subject a clathrin-dependent endocytosis inhibitor in an amount sufficient to enhance TGF- ß signaling. In another aspect, the invention is directed to a method of treating a condition associated with decreased TGF- ß signaling in a patient in need thereof comprising administering to said patient a clathrin-dependent endocytosis inhibitor in a therapeutically effective amount.