发明名称 NOVEL PYRIDINE DERIVATIVES AND PYRIMIDINE DERIVATIVES (3)
摘要 A compound represented by the following formula, or a salt thereof or a hydrate of the foregoing, has excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity, and cancer metastasis inhibitory activity. R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents —CH═, nitrogen or the like.
申请公布号 US2010075944(A1) 申请公布日期 2010.03.25
申请号 US20090558982 申请日期 2009.09.14
申请人 MATSUSHIMA TOMOHIRO;TAKAHASHI KEIKO;FUNASAKA SETSUO;OBAISHI HIROSHI;SHIROTORI SHUJI 发明人 MATSUSHIMA TOMOHIRO;TAKAHASHI KEIKO;FUNASAKA SETSUO;OBAISHI HIROSHI;SHIROTORI SHUJI
分类号 A61K31/4545;A61K31/397;A61K31/496;A61K31/5377;A61P35/00;C07D401/12;C07D401/14;C07D413/12 主分类号 A61K31/4545
代理机构 代理人
主权项
地址