发明名称 |
METHOD FOR DIAGNOSIS OF AND FOLLOWING A BACTERIAL VAGINOSIS BY MOLECULAR QUANTIFICATION |
摘要 |
The present invention relates to a method for in vitro diagnosis and follow-up of vaginal bacterial flora status in relation to the presence of bacterial vaginosis, and for monitoring its treatment where applicable, wherein the presence of bacterial vaginosis or failure of on-going treatment is determined if the concentrations of specific sequences present in a single copy in the DNA of the bacteria Atopobium vaginae and Gardnerella vaginalis in the DNA extracted from a vaginal discharge specimen from a patient are such that at least one of the following two conditions a) and b) are met: a) the concentration Ca of said DNA fragment of Atopobium vaginae is greater than or equal to 108 copies/mL, and b) the concentration Cg of said DNA fragment of Gardnerella vaginalis is greater than or equal to 109 copies/mL.
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申请公布号 |
US2010075306(A1) |
申请公布日期 |
2010.03.25 |
申请号 |
US20070312711 |
申请日期 |
2007.11.20 |
申请人 |
UNIVERSITE DE LA MEDITERRANEE (AIX-MARSEILLE II) |
发明人 |
BRETELLE FLORENCE;FENOLLAR FLORENCE;HENRY-MARY MIREILLE;MENARD JEAN-PIERRE;RAOULT DIDIER |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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