发明名称 |
HYPERBRANCHED POLYMERS AND THEIR APPLICATIONS |
摘要 |
<p>The present invention provides a branched, a dendritic, or a hyperbranched poly(amino ester) having a polymer backbone comprising a plurality of branches, wherein the polymer backbone has at least one secondary and at least one tertiary amine linkage. Branched poly(amino ester)s are prepared via a Michael addition reaction of a tris(acrylate ester)monomer with a diamine monomer. In one aspect, the diamine monomer has a primary amino group and a secondary amino group. The poly(amino ester) compounds can be end-capped by reacting with a suitable agent. The present invention also provides applications including, but are not limited to, the delivery of bioactive agents, such as drugs, DNA or RNA; or biocompatible imaging.</p> |
申请公布号 |
EP1874844(A4) |
申请公布日期 |
2010.03.24 |
申请号 |
EP20060733552 |
申请日期 |
2006.04.28 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
HE, CHAOBIN;WU, DECHENG;LIU, YE |
分类号 |
C08G63/685;A61K47/30;A61K47/34;A61K47/48;A61K48/00;A61K49/00;A61K49/04;A61K49/12;C08G63/40;C08G73/02;C08G83/00;C12N15/87 |
主分类号 |
C08G63/685 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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