发明名称 NONLINEAR OPTICAL DETECTION OF MOLECULES COMPRISING AN UNNATURAL AMINO ACID POSSESSING A HYPERPOLARIZABILITY
摘要 A system for making molecules, and proteins in particular, suitable for detection by a surface-selective nonlinear optical technique. A first use of the invention is for determining a protein's structure in real space and real time. A second use of the invention is to detect a protein or its activity (conformational change). A third use of the invention is for drug screening. A further aspect of the present invention is measuring probe tilt angle orientation in an oriented protein.
申请公布号 US2010068144(A1) 申请公布日期 2010.03.18
申请号 US20090535631 申请日期 2009.08.04
申请人 SALAFSKY JOSHUA S 发明人 SALAFSKY JOSHUA S.
分类号 A61K49/00;A61P43/00;C12N5/00;C12N15/74;G01N33/53 主分类号 A61K49/00
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