摘要 |
<p>The present invention relates to compositions and methods for promoting and enhancing the analgesic, anesthetic and anticonvulsant properties of epoxygenated fatty acids, in particular, epoxy-eicosatrienoic acids ("EETs") and inhibitors of soluble epoxide hydrolase ("sEH") in the presence of elevated levels of cyclic adenosine monophosphate ("cAMP") by combining or co-administering the epoxygenated fatty acid, EET and/or inhibitor of sEH with an agent that increases intracellular levels of cAMP, e.g., a phosphodiesterase inhibitor.</p> |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;HAMMOCK, BRUCE, D.;INCEOGLU, A., BORA;JINKS, STEVEN, L. |
发明人 |
HAMMOCK, BRUCE, D.;INCEOGLU, A., BORA;JINKS, STEVEN, L. |