发明名称 OPTIMIZATION OF CROSSOVER POINTS FOR DIRECTED EVOLUTION
摘要 Methods and devices for more efficiently engineering diversity into recombinant polypeptides and/or nucleic acids are provided herein. For example, a variety of methods of selecting and/or assessing potential crossover sites in an amino acid sequence or a nucleotide sequence are provided, as well as the resulting chimeric product sequences. These methods include, e.g., consideration of structural, functional and/or statistical data in the selection and assessment of sequences and crossover sites for use in recombination.
申请公布号 US2010070192(A1) 申请公布日期 2010.03.18
申请号 US20090557434 申请日期 2009.09.10
申请人 MAXYGEN, INC. 发明人 MUNDORFF EMILY C.;GOVINDARAJAN SRIDHAR;GUSTAFSSON CLAES;MINSHULL JEREMY S.
分类号 G06N3/00;C12N;C12Q1/68;C40B50/02;G01N33/48;G01N33/50;G01N33/53;G06F17/00;G06F17/10;G06F17/11;G06F19/16;G06F19/22 主分类号 G06N3/00
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