发明名称 |
COMPOSITIONS AND METHODS FOR THE PREVENTION OF OXIDATIVE DEGRADATION OF PROTEINS |
摘要 |
The invention relates to pharmaceutical formulations comprising a protein and free methionine in combination with one or more compounds capable of preventing the oxidation of aromatic amino acid residues within a protein. More specifically, the invention relates to stabilized, pharmaceutically effective preparations of oxidation-sensitive therapeutic agents. The invention further relates to a method of inhibiting the oxidation of such therapeutic agents.
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申请公布号 |
CA2734275(A1) |
申请公布日期 |
2010.03.18 |
申请号 |
CA20092734275 |
申请日期 |
2009.09.09 |
申请人 |
GENENTECH, INC. |
发明人 |
JI, JUNYAN A.;WANG, YUCHANG JOHN;ZHANG, BOYAN |
分类号 |
A61K38/29;A61K47/18 |
主分类号 |
A61K38/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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