COMPLEMENT FACTOR H-BASED ASSAYS FOR SERUM BACTERICIDAL ACTIVITY AGAINST NEISSERIA MENINGITIDIS
摘要
<p>Assays for detection of bactericidal anti-Neisserial antibodies using a factor H polypeptide having a human amino acid sequence that mediates binding to Neisserial factor H binding protein (fhBp) are provided, as well as non-human animal models of Neisserial infection.</p>
申请公布号
WO2010027872(A1)
申请公布日期
2010.03.11
申请号
WO2009US55086
申请日期
2009.08.26
申请人
CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND;GRANOFF, DAN M.;WELSCH, JO ANNE;RAM, SANJAY;THE UNIVERSITY OF MASSACHUSSETTS;NOVARTIS VACCINES & DIAGNOSTICS, INC.
