发明名称 |
Detection of Histone Deacetylase Inhibition |
摘要 |
Provided are compositions and methods for intracellular detection of enzyme activity. One example of a composition is a histone deacetylase substrate comprising a compound of the following formula (I): One example of a method is a method for detecting histone deacetylase activity comprising introducing a compound according to formula (1) to a plurality of cells and monitoring the cells with magnetic resonance spectroscopy.
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申请公布号 |
US2010062465(A1) |
申请公布日期 |
2010.03.11 |
申请号 |
US20070297832 |
申请日期 |
2007.04.20 |
申请人 |
RONEN SABRINA M;GELOVANI JURI G;BORNMANN WILLIAM G;PANG JIHAI;PAL ASHUTOSH;TONG WILLIAM P;PAZ ASHUTOSH;MAXWELL DAVID S;SANKARANARAYANAPILLAI MADHURI |
发明人 |
RONEN SABRINA M.;GELOVANI JURI G.;BORNMANN WILLIAM G.;PANG JIHAI;PAL ASHUTOSH;TONG WILLIAM P.;PAZ ASHUTOSH;MAXWELL DAVID S.;SANKARANARAYANAPILLAI MADHURI |
分类号 |
C12Q1/34;C07C233/01;C07C271/10;C07F7/22 |
主分类号 |
C12Q1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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