发明名称 Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof
摘要 The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3, R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is —C(O)—R10, -A1-C(O)—R10, —O-A2-C(O)—R10 or a tetrazol-5-yl group, which exhibit potent and selective &bgr;3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
申请公布号 US7674938(B2) 申请公布日期 2010.03.09
申请号 US20070936680 申请日期 2007.11.07
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 KOBAYASHI JUNICHI;NAKAMURA TETSUYA;SUZUKI RITSU;MURANAKA HIDEYUKI;OZAWA TOMONAGA;KAI YUICHIRO;ISHIKAWA TAKEHIRO;KONDO TATSUHIRO;TAMAI TETSURO;AKAHANE SATOSHI
分类号 C07C217/14;A61K31/195;A61P1/00;A61P1/16;A61P3/04;A61P3/06;A61P3/10;A61P13/00;C07C217/20;C07D307/79 主分类号 C07C217/14
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