| 发明名称 |
Process for the resolution of enantiomers of (3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-trien-7-yl) nitrile and application in the synthesis of ivabradine |
| 摘要 |
Process for the optical resolution of the compound of formula (I): by chiral chromatography. Application in the synthesis of ivabradine, of its addition salts with a pharmaceutically acceptable acid and of their hydrates.
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| 申请公布号 |
US2010056778(A1) |
申请公布日期 |
2010.03.04 |
| 申请号 |
US20090583632 |
申请日期 |
2009.08.24 |
| 申请人 |
LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;DRON DANIEL;GOJON ERIC;PHAN MARYSE |
发明人 |
LERESTIF JEAN-MICHEL;LECOUVE JEAN-PIERRE;DRON DANIEL;GOJON ERIC;PHAN MARYSE |
| 分类号 |
C07D223/14;C07C211/00;C07C255/00 |
主分类号 |
C07D223/14 |
| 代理机构 |
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