| 摘要 |
The present invention relates to expression of CXCR4 in mesenchymal stem cells (MSCs) and homing of MSCs to sites of injury. In particular, the invention provides expanded cultures of MSCs which maintain cell surface expression of CXCR4. The MSCs are capable of homing to sites of injury and are suitable for treatment of ischemic disorders, including cardiac disorders, bone and cartilage disorders, liver disorders, inflammatory disorders, and stroke. |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;DORONIN, SERGEY, V.;POTAPOVA, IRINA, A.;COHEN, IRA, S.;ROSEN, MICHAEL, R.;ROBINSON, RICHARD, B.;BRINK, PETER, R. |
发明人 |
DORONIN, SERGEY, V.;POTAPOVA, IRINA, A.;COHEN, IRA, S.;ROSEN, MICHAEL, R.;ROBINSON, RICHARD, B.;BRINK, PETER, R. |
