发明名称 |
Method for the suppression of visceral pain by regulating T-type calcium channel |
摘要 |
The disclosure concerns a method for the suppression of visceral pain by regulating the T-type calcium channel; a visceral pain inhibitor that includes a T-type calcium channel inhibitor as an effective ingredient; and a method of screening a visceral pain inhibitor by investigating the suppression activity of T-type calcium channels. Particularly, the present invention relates to a method for the suppression of visceral pain by regulating an alpha 1G T-type calcium channel in the central nervous system and alpha 1H and alpha 1I T-type calcium channels in the peripheral nervous system; a visceral pain inhibitor that includes a T-type calcium channel inhibitor as an effective ingredient; and a method of screening a visceral pain inhibitor by investigating the suppression activity of T-type calcium channels. The method of the present invention can be effectively used to suppress visceral pain by regulating T-type calcium channel in a precise mechanism without any side effects.
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申请公布号 |
US7670791(B1) |
申请公布日期 |
2010.03.02 |
申请号 |
US20070753108 |
申请日期 |
2007.05.24 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
SHIN HEE-SUP;KIM DAE-SOO;KIM CHAN-KI |
分类号 |
G01N33/50;G01N33/53;A61K31/00;A61K31/4184;A61K33/00;A61K33/24;A61K45/00;A61P1/00;A61P25/00;A61P25/02;A61P25/04;A61P29/00;A61P43/00;G01N33/15;G01N33/566;G01N33/567;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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