Methoden um Rotavirusvarianten zu Trennen und lebender attenuierter Rotavirus Impfstoff
摘要
<p>The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43. The invention further provides a novel formulation for a rotavirus vaccine which is in the form of a quick dissolving tablet for immediate dissolution when placed on the tongue.</p>
申请公布号
DE60043676(D1)
申请公布日期
2010.02.25
申请号
DE2000643676
申请日期
2000.08.15
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A., RIXENSART
发明人
COLAU, BRIGITTE DESIREE A.;DENAMUR, FRANCOISE;KNOTT, ISABELLE;POLISZCZAK, ANNICK;THIRY, GEORGES;VANDE VELDE, VINCENT