| 发明名称 |
ANTISENSE MODULATION OF CLUSTERIN EXPRESSION |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an antisense compound, a composition and a method which modulate the expression of clusterin. <P>SOLUTION: The composition includes an antisense compound targeted to a nucleic acid encoding for clusterin, particularly an antisense oligonucleotide. The method includes using the compound for the treatment of diseases associated with the modulation of clusterin expression and the expression of clusterin. <P>COPYRIGHT: (C)2010,JPO&INPIT |
| 申请公布号 |
JP2010043086(A) |
申请公布日期 |
2010.02.25 |
| 申请号 |
JP20090191924 |
申请日期 |
2009.08.21 |
| 申请人 |
ISIS PHARMACEUTICALS INC |
发明人 |
MONIA BRETT P;FREIER SUSAN M |
| 分类号 |
A61K31/7088;C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/06;A61P9/00;A61P9/10;A61P13/12;A61P25/28;A61P27/02;A61P35/00;A61P43/00;C12N15/113 |
主分类号 |
A61K31/7088 |
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