发明名称 |
Chemical reaction device, chemical reaction system and chemical reaction method |
摘要 |
A chemical reaction device is provided for a chemical reaction between molecules immobilized on a solid phase and molecules in a solution, and a chemical analysis device is also provided to capture molecules in the solution by molecules immobilized on the solid phase through a chemical reaction and subsequent measurement of the captured molecules. Reaction efficiency as well as sample throughput are thereby improved. The chemical reaction device and the chemical analysis device use a channel of a microfluidic device for a reaction vessel, and at least a particular molecule is immobilized on an interior surface and a fixed structure or a non-fixed obstacle against a flow is provided in the channel. In a typical reaction vessel having an enzyme immobilized on an interior surface of a capillary and glass beads functioning as an obstacle for the flow filled in the channel of the capillary, a reaction solution can move either in one direction or back and forth in two directions to thereby undergo a reaction with the enzyme immobilized on the interior surface. The flow of the reaction solution is not a laminar flow so that a reaction between the particular molecule immobilized and the reaction solution proceeds at high efficiency.
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申请公布号 |
US7666662(B2) |
申请公布日期 |
2010.02.23 |
申请号 |
US20040854018 |
申请日期 |
2004.05.26 |
申请人 |
HITACHI, LTD. |
发明人 |
KOHARA YOSHINOBU;OKANO KAZUNORI;NODA HIDEYUKI |
分类号 |
C12M1/34;G01N33/53;C12M1/00;C12N15/09;G01N33/543;G01N37/00 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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