发明名称 |
HIV vaccines based on Env of multiple clades of HIV |
摘要 |
In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.
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申请公布号 |
US7666427(B2) |
申请公布日期 |
2010.02.23 |
申请号 |
US20070818113 |
申请日期 |
2007.06.13 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
NABEL GARY J.;CHAKRABARTI BIMAL;KONG WING-PUI;HUANG YUE;YANG ZHI-YONG |
分类号 |
A61K39/00;A61K39/21;C07K14/16 |
主分类号 |
A61K39/00 |
代理机构 |
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