摘要 |
<P>PROBLEM TO BE SOLVED: To provide a compound or its pharmaceutically acceptable salt useful as a therapeutic and/or preventive agent for diseases related to CaMKII such as autoimmune diseases. Ž<P>SOLUTION: The compound is a condensed pyrimidine compound represented by formula (1) [wherein R<SP>1</SP>is hydrogen, an alkyl group or the like; R<SP>2</SP>is a substituted or nonsubstituted aryl group or the like, X is represented by formula (2) (wherein m is an integer of 0-5, Cy is a substituted or nonsubstituted phenyl or the like; and R<SP>4</SP>and R<SP>5</SP>are each hydrogen or the like), Y is NH, oxygen or the like and the ring A is a carbon ring, an N-containing heterocycle or the like] and includes its pharmacologically acceptable salt. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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