发明名称 |
Compositions and methods of preparation of liposomal microparticulate IL-12 |
摘要 |
This invention provides methods and compositions for localized delivery of IL-12 to a desired site. The composition comprises liposomes carrying IL-12. The liposomes comprise phosphatidyl choline, phosphatidyl glycerol and cholesterol. The size and composition of the liposomes is such that there is minimal leakage into the systemic circulation. These compositions can be used for delivery of IL-12 to selected sites such as tumors.
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申请公布号 |
US7662405(B2) |
申请公布日期 |
2010.02.16 |
申请号 |
US20060502206 |
申请日期 |
2006.08.09 |
申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK |
发明人 |
BALU-IYER SATHY V.;BANKERT RICHARD B.;PUROHIT VIVEK S. |
分类号 |
A61K9/127;A61K45/00 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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