| 摘要 |
<P>PROBLEM TO BE SOLVED: To identify functional polymorphisms of the IL-1 locus affecting transcription or expression of the one or more IL-1 genes. <P>SOLUTION: Provided is the method for detecting a polymorphism associated with in an upstream region of the interleukin-1β (IL-B) gene (IL-1B (-3737)) that affects transcription of the gene and susceptibility to inflammatory and infectious diseases such as periodontal disease and Alzheimer's disease. <P>COPYRIGHT: (C)2010,JPO&INPIT |
