| 摘要 |
PURPOSE: A composition containing a compound isolated from Dryopteris crassirhizoma NAKAI extract for preventing and treating AIDS is provided to ensure suppression effects to the activation of HIV-1 protease and use as a pharmaceutical composition and health functional food. CONSTITUTION: A compound isolated from Dryopteris crassirhizoma NAKAI extract is denoted by general formula (a). In general formula (a), R1 is hydrogen atom, hydroxyl group, acetate group, halogen atom, low alkyl group of C1-C4, low alkyl ester or low alkyl carboxy group. A compound isolated from the Dryopteris crassirhizoma NAKAI extract is denoted by general formula (b). A pharmaceutical composition for preventing and treating AIDS contains the novel compound of general formula (a) or (b) or its pharmaceutically acceptable salt as an active ingredient. A health functional food for preventing and treating AIDS contains the novel compound of general formula (a) or (b) or its pharmaceutically acceptable salt as an active ingredient.
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