发明名称 |
Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems |
摘要 |
Fluorophores derived from photoactivatable azide-pi-acceptor fluorogens or from a thermal reaction of an azide-pi-acceptor fluorogen with an alkene or alkyne are disclosed. Fluorophores derived from a thermal reaction of an alkyne-pi-acceptor fluorogen with an azide are also disclosed. The fluorophores can readily be activated by light and can be used to label a biomolecule and imaged on a single-molecule level in living cells.
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申请公布号 |
US2010029952(A1) |
申请公布日期 |
2010.02.04 |
申请号 |
US20090454273 |
申请日期 |
2009.05.13 |
申请人 |
KENT STATE UNIVERSITY;LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
TWEG ROBERT J.;MOERNER WILLIAM E.;LORD SAMUEL J.;LIU NA;SAMUEL REICHEL |
分类号 |
C07D213/02;C07D249/04;C07D271/12;C07D307/02 |
主分类号 |
C07D213/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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