ANALYTE SENSOR APPARATUSES HAVING IMPROVED ELECTRODE CONFIGURATIONS AND METHODS FOR MAKING AND USING THEM

摘要

Glucose sensor for implantation within a mammal, the analyte sensor comprising a flexible substrate, a conductive layer disposed on the substrate and comprising a reference electrode, a working electrode and a counter electrode. The sensor further comprises an analyte sensing layer, an analyte modulating layer and a cover layer disposed on the analyte sensor apparatus, wherein the cover layer comprises an aperture positioned on the cover layer so as to facilitate an analyte present in the mammal contacting and diffusing through the analyte modulating layer and contacting the analyte sensing layer. The device further comprises a processor for noise reduction and data processing A fuse element for avoiding overuse, circuitry for generating a pulsed sensing current and means for sensing if the sensor is sufficiently hydrated. Typical embodiments of the invention include glucose sensors used in the management of diabetes.