发明名称 |
NOVEL PROCESS FOR DEVITALIZED/ACELLULAR TISSUE FOR TRANSPLANTATION |
摘要 |
A method for processing tissue to produce a devitalized acellular matrix for transplantation comprises soaking the tissue in a first processing solution having a pH below 7 to reduce protease activity, periodically infusing ozone into the first processing solution to devitalize the tissue and reduce bioburden, and soaking the tissue in a second processing solution to remove cellular debris. The present invention also includes a system for processing the tissue. The devitalized acellular matrix acts as a scaffold for cellular ingrowth when transplanted into a recipient to form new tissue.
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申请公布号 |
US2010028849(A1) |
申请公布日期 |
2010.02.04 |
申请号 |
US20070311964 |
申请日期 |
2007.10.18 |
申请人 |
SHELBY NANCY JANE;FITZPATRICK KRISTIN LEIGH;HOLMES DARREL LEE |
发明人 |
SHELBY NANCY JANE;FITZPATRICK KRISTIN LEIGH;HOLMES DARREL LEE |
分类号 |
A01N1/02;C12N9/99 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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