Provided are compositions and methods for preventing, treating, ameliorating or diagnosing conditions or diseases involving a myeloid cell proliferation disorder. Such compositions and methods target miRNA function myeloproliferative diseases. More particularly, such compositions and methods target miR-29a function in myeloid cell proliferation disorders. Also provided are methods for diagnosing risk or presence of a myeloid cell proliferation disorder in a subject.
申请公布号
WO2009137801(A3)
申请公布日期
2010.02.04
申请号
WO2009US43353
申请日期
2009.05.08
申请人
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;GU, HUA;HAN, YOON-CHI;PARK, CHRISTOPH;WEISSMAN, IRVING