摘要 |
Indirubin derivatives of formula I
wherein
R represents -(A) n - R 1 or -CO-N(R 2 ,R 3 ) with
€¢ A being C1-C5 alkylene group, optionally substituted by one or several A 1 radical, A 1 being an halogen Br, OH, OR 4 or NH 2 , R 4 being C1-C5 alkyl;
€¢ R 1 being halogen, OH, N(R 2 , R 3 ); R 2 and R 3 , identical or different, being C1-C5 alkyl, optionally substituted by A 1 such as above defined, or R 2 and R 3 are part of a cycle with 5 or 6 elements optionally comprising another heteroatom such as O or N;
€¢ n = 1-5. It also relates to the biological application thereof. |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
MEIJER, LAURENT;SKALTSOUNIS, LEANDROS;MIKROS, EMMANUEL;MAGIATIS, PROKOPIOS;JOHNSON, CARL |