Substituted aminoalkyl- and amidoalkyl-benzopyran derivatives

摘要

Disclosed are aminoalkyl- and amidoalkyl-benzopyran derivatives of formula (I) and the pharmaceutically acceptable salts thereof, wherein the variables are as defined in the specification. These compounds are active as selective and reversible monoamine oxidase type B (MAO-B) inhibitors in vitro and in vivo and are suitable for the prevention and treatment of CNS degenerative disorders including Parkinson's disease, Alzheimer's disease, restless leg syndrome, epilepsy, amylotrophic lateral sclerosis, stroke, attention deficit hyperactivity disorders, drug addiction, smoking cessation or obesity.