发明名称 |
NOVEL PROCESS FOR PREPARATION OF O-DESMETHYLVENLAFAXINE |
摘要 |
<p>The present invention relates to the novel processes for the preparation of 4-(2- (dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol, commonly known as O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof The present invention also relates to the novel process for the preparation of O- desmethylvenlafaxine of formula (I) and its pharmaceutically acceptable salts thereof formula (V) or formula (VI) formula (I) or formula (VII) wherein, R is hydrogen, methoxyethoxymethyl (MEM), methoxymethyl (MOM), aryloyl, arylsulfonyl, tetrahydropyranyl or substituted silyl.</p> |
申请公布号 |
WO2009084037(A4) |
申请公布日期 |
2010.01.21 |
申请号 |
WO2008IN00850 |
申请日期 |
2008.12.19 |
申请人 |
CALYX CHEMICALS AND PHARMACEUTICALS LTD.;LAL, BANSI;GUND, VITTHAL, GENBHAU;PANDIAN, VIJAY, KANNAN |
发明人 |
LAL, BANSI;GUND, VITTHAL, GENBHAU;PANDIAN, VIJAY, KANNAN |
分类号 |
C07C209/00;C07C13/00;C07C215/00 |
主分类号 |
C07C209/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|