发明名称 |
DIAGNOSTICS FOR MEMBRANOUS NEPHROPATHY |
摘要 |
The invention relates to immunoassays, reagents, therapeutics and methods of diagnosing and prognosis evaluation of idiopathic membranous nephropathy (MN). Immunoassays comprise enzyme-linked immunoabsorbent assays and nephelometric immunoassays for serum auto-antibodies reactive against a phospholipase A2 receptor (PLA2R). Therapeutic methods include removal of the auto-antibodies by adsorbance or administration of soluble PLA2R or fragments to sequester the auto-antibodies.
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申请公布号 |
CA2731065(A1) |
申请公布日期 |
2010.01.21 |
申请号 |
CA20092731065 |
申请日期 |
2009.07.20 |
申请人 |
BOSTON MEDICAL CENTER CORPORATION;LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
SALANT, DAVID J.;BECK, LAURENCE H.;LAMBEAU, GERARD |
分类号 |
G01N33/564;G01N33/68 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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地址 |
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