METHOD FOR DIAGNOSING AND TREATING EMPHYSEMA

摘要

The present invention provides methods for diagnosing a patient with emphysema or COPD by detecting the levels of EMAP Il in a sample. Alternatively, methods are provided for determining the susceptibility of a patient to develop emphysema or COPD by detecting the levels of EMAP Il in a sample. The levels of EMAP Il may be determined by immunoassay techniques. The present invention also provides methods for treating patients with emphysema or COPD by administering a therapeutically effective amount of an EMAP Il neutralizing compound. The compound may be an antibody, siRNA, antisense RNA or an antagonist of CXCR3.