发明名称 VERFAHREN ZUM HERSTELLEN EINER NAHTLOSEN KAPSEL
摘要 Disclosed is a method of manufacturing a spherical seamless capsule formed by encapsulating a filler material such as a medicine with a capsule shell material such as gelatin. A concentric multiple nozzle is positioned above the liquid surface of a curing liquid such that the tip of the nozzle faces down. A concentric columnar composite flow which is discharged from this concentric multiple nozzle and which is composed of a filler material and a capsule shell material outside the filler material is immersed in the curing liquid, and cut in the curing liquid to form a droplet. The capsule shell material of the droplet is cured by the curing liquid, and thereby a seamless capsule is formed. Since the droplet is not dropped into the curing liquid, no deformation of the droplet caused by collision against the liquid surface occurs. The tip of the multiple nozzle is positioned above the liquid surface of the curing liquid. This prevents water contained in the curing liquid from adhering to the surface of the nozzle and penetrating into the composite flow. <IMAGE>
申请公布号 AT452618(T) 申请公布日期 2010.01.15
申请号 AT20010956914T 申请日期 2001.08.16
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 NAKAJIMA, HIROYUKI;YAMAZAKI, MASAYOSHI;NAKAMURA, TAKESHI;YAMAMOTO, TSUKASA
分类号 A61J3/07;A61K9/48;A61K9/50;B01J13/14 主分类号 A61J3/07
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