摘要 |
The present invention relates to a method for predicting or designing, detecting, and/or verifying a novel cell-penetrating peptide (CPP) and to a method for using said new CPP and/or a novel usage of a known CPP for an improved cellular uptake of a cellular effector, coupled to said CPP. Furthermore, the present invention also relates to a method for predicting or designing, detecting and/or verifying a novel cell-penetrating peptide (CPP) that mimics cellular effector activity and/or inhibits cellular effector activity. The present invention additionally relates to the use of said CPP for treating and/or preventing a medical condition and to the use of said CPP for the manufacture of a pharmaceutical composition for treating a medical condition. |
申请人 |
CEPEP II AB |
发明人 |
HAELLBRINK, MATTIAS;POOGA, MARGUS;METSIS, MADIS;KOGERMAN, PRIIT;VALKNA, ANDREAS;MEIKAS, ANNE;LINDGREN, MARIA;GRAESLUND, ASTRID;ERIKSSON, GOERAN;OESTENSSON, CLAES, GOERAN;BUDIHNA, METKA;ZORKO, MATJAZ;ELMQUIST, ANNA;SOOMETS, URSEL;LUNDBERG, PONTUS;JAERVER, PETER;SAAR, KUELLIKI;EL-ANDALOUSSI, SAMIR;KILK, KALLE;LANGEL, ULO |