The present invention relates to the field of pain management, and more particularly to synergistic codrugs comprising an opioid and nornicotine which have been combined to form a single chemical codrug entity. When the codrug is administered it produces a synergistic analgesic response to pain.
申请公布号
WO2009121018(A4)
申请公布日期
2010.01.14
申请号
WO2009US38664
申请日期
2009.03.27
申请人
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION;HOLTMAN, JOSEPH, R.;CROOKS, PETER, A.;CHAKRABORTY, UJJWAL