发明名称 CYCLOPEPTIDES USED AS MMP-TYPE PROTEASE ENZYME INHIBITORS
摘要 The invention relates to a cyclopeptide of the following formula: wherein: - S1 is a target peptide sequence of an MMP enzyme, that is a peptide sequence that can be identified and cleaved by an MMP enzyme; - M1 and M2 are independently a single bond, a hydrocarbonated group or an amino acid residue, optionally carrier of an aromatic side group; - X and Y are independently a single bond, and a linear or branched hydrocarbonated group that can have, in its chain, at least one heteroatom or an amino acid residue. Said cyclopeptides can be used as MMP protease enzyme inhibitors.
申请公布号 WO2010000592(A2) 申请公布日期 2010.01.07
申请号 WO2009EP57202 申请日期 2009.06.10
申请人 COMMISSARIAT A L'ENERGIE ATOMIQUE;UNIVERSITE VICTOR SEGALEN - BORDEAUX 2;BERTHELOT, THOMAS;DELERIS, GERARD 发明人 BERTHELOT, THOMAS;DELERIS, GERARD
分类号 C07K7/50;C07K7/64;C12Q1/37 主分类号 C07K7/50
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