发明名称 |
CYCLOPEPTIDES USED AS MMP-TYPE PROTEASE ENZYME INHIBITORS |
摘要 |
The invention relates to a cyclopeptide of the following formula: wherein: - S1 is a target peptide sequence of an MMP enzyme, that is a peptide sequence that can be identified and cleaved by an MMP enzyme; - M1 and M2 are independently a single bond, a hydrocarbonated group or an amino acid residue, optionally carrier of an aromatic side group; - X and Y are independently a single bond, and a linear or branched hydrocarbonated group that can have, in its chain, at least one heteroatom or an amino acid residue. Said cyclopeptides can be used as MMP protease enzyme inhibitors. |
申请公布号 |
WO2010000592(A2) |
申请公布日期 |
2010.01.07 |
申请号 |
WO2009EP57202 |
申请日期 |
2009.06.10 |
申请人 |
COMMISSARIAT A L'ENERGIE ATOMIQUE;UNIVERSITE VICTOR SEGALEN - BORDEAUX 2;BERTHELOT, THOMAS;DELERIS, GERARD |
发明人 |
BERTHELOT, THOMAS;DELERIS, GERARD |
分类号 |
C07K7/50;C07K7/64;C12Q1/37 |
主分类号 |
C07K7/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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