ANTIGEN SCREENING SYSTEM

摘要

The invention comprises methods and compositions for identifying antigens of human lymphocytes as well as compositions including the antigens and methods of using the antigens The invention also features methods of evaluating an immune response in a human subject, e.g., for diagnostic applications. In certain embodiments, a library of cells comprising heterologous polypeptides is contacted with a first group of cells, which are subsequently contacted with lymphocytes, and the immune response of the lymphocytes is measured to determine epitopes related to cell mediated immunity.