摘要 |
<p>Method for the preparation of tricyclic amines of the general formula (I) and salts thereof with pharmaceutically acceptable acids. where R1 = hydrogen or methyl, R = chlorine or fluorine, R2 and R3 hydrogen, chlorine or fluorine, X = ethylene or vinylene group, the latter opt. substd. by a halogen atom. The exocyclic double bond of the centre ring may be opt. hydrogenated. The compounds are antidepressants, narcotic potentiators, adrenolytic, sedative, antihistamine and local anaesthetic active.</p> |