发明名称 Drugs for chronic pain
摘要 The present invention relates to nitrooxyderivatives or salts thereof having the following general formula (I): R-NR1c-(K)k0-(B)b0-(C)c0-NO2 (I) wherein c0, b0 and k0 are 0 or 1; R is the radical of an analgesic drug for chronic pain, for instance neurophatic pain; R1c is H or alkyl with from 1 to 5 carbon atoms; B is such that its precursor is selected from amino acids, hydroxy acids, polyalcohol, compounds; C is a bivalent radical containing an aliphatic, heterocyclic or aromatic radical.
申请公布号 US7642289(B2) 申请公布日期 2010.01.05
申请号 US20050537439 申请日期 2005.06.16
申请人 NICOX S.A. 发明人 ONGINI ENNIO;ALMIRANTE NICOLETTA;DEL SOLDATA PIERO
分类号 A61K31/16;A61K31/166;A61P29/00;C07C229/04;C07C229/28;C07C235/12;C07C235/42;C07C271/22;C07C271/54 主分类号 A61K31/16
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